Terrific! I got rabbit-holed on OREO1ATreat that's twisted (to savor the dark sides!)[----] for a while, and started looking for things to twist- then connected with the "Saw the opposite way?" clue... together, that had me thinking - OK, let's find answers that are still words when reversed. And there are a lot... enough to make me think this is a good path. ARE, SAID, PLUG, SAW, LONE, TROW, LIVED, RATER, USED, and PEEK. Furthermore, a number of these stand out as somewhat "weird" grid entries- DESU50Dwww.____.edu (HBCU in Dover)[----], RETAR43DRepair a road or a roof[-----], WORT12DSt. John's herbal remedy[----], DIAS50A"Buenos ____!" ("Good day!")[----], and ENOL11DHydroxyl compound[----] are all- at the very least- uncommonly used grid entries.
Well, I'm sad to report... all of those grid entries and their clues do absolutely nothing together! LOL.