Well, as the clues are symmetric, the E must come for reflected equivalent as the place where the D came from.
Well, the thing about noise... once I get the meta in place I then have to put in the rest of the clues as an afterthought. But it's on afterthought that makes up 85% of the final puzzle. Unintentional noise gets in. I can see the issue with "pillage" but what's wrong with "genus" of "muggle".