Very nice! I had to spam a little bit to get the second G in GIGUE but I think I ought to have known IGA. I loved the ORIGINALITY in the clue for ABAAB!
It's in the Moderna vaccine, and in the name of the Moderna vaccine
34A
Qualified
36A
Words uttered wistfully while sending your baby off to college, perhaps
38A
Monty Python title character who's not the Messiah, he's a very naughty boy
40A
"Hometown proud" supermarket chain
41A
MayPac, e.g.
42A
"Clean up on ________!"
44A
Light
45A
Burglar deterrent letters
46A
Other than that
47A
"Hamilton" number in which Eliza sets fire to the letters Alexander wrote her
49A
Next to
51A
Homer Simpson's cry
52A
Computing pioneer Lovelace
55A
What Mrs. Basil E. Frankweiler had in a classic children's novel by E. L. Konigsburg... and what three of this puzzle's entries have in their circled squares
59A
"_____ 14A fits..."
62A
It's striped on a zebra
63A
Word with heat or kitchen
64A
"___ me!"
65A
A single time
66A
Suffix with cigar or bachelor
67A
Lawman Earp
68A
Ooze
69A
Looked over
Down
1D
German industrialist Schindler
2D
"Holding Out for ___" (1984 Bonnie Tyler hit)
3D
Staple jokes for David Letterman
4D
Funnyman Meyers or MacFarlane
5D
Exercises started from a supine position
6D
Like many surnames starting with "O"
7D
HOV ____
8D
A new one might get turned over
9D
Doesn't quite seem right
10D
SATs or ACTs
11D
Besmirch
12D
Knee joint, briefly
13D
Pigpen
21D
Town where you can see a Thunder game, or website where you can find a date to a Thunder game: Abbr.
22D
Brusque response to "Can I fix you something?"
26D
Trait valued in crossword construction
27D
Pharmacist's photo developing time frame: Abbr.
28D
"_____, brutish, and short": Thomas Hobbes quote
30D
Ring
31D
Sprightly Baroque dance
32D
Actor Sharif or Epps
34D
An awkward entry, / So it would seem. / But in any cent'ry / Well-read gentry / Know this rhyme scheme.
35D
One of two at Jodie Foster's wedding
36D
Argentine uncles
37D
Untruthful one
39D
Lacking the most
43D
"Weird ____ but OK" (meaning "most people wouldn't brag about that")
47D
Woody's "Toy Story 4" love interest
48D
Cult film starring "Weird Al" Yankovic
50D
Injured soldier's cry
51D
Fool with a pointy cap
53D
Al ___ (pasta style)
54D
Inquired
56D
My Chemical Romance fans
57D
Scooby-Doo is a Great one
58D
Words sometimes said slowly while stroking one's chin