Just to make sure I wasn't missing anything: is there anything tying each pair together, or were the pairings based on which virtue and which signal were in corresponding places in the grid?
"The evidence of things not seen," per the New Testament (43A)
42A
"___ the season..."
43A
BBC inspector Endeavour (40A)
44A
Scottish girl
46A
Fed Chair Jerome
47A
Colonizer of sorts
48A
"Science Guy" Bill
50A
Menu lead-in to mode
51A
"You've got mail" co.
52A
Summer coolers
53A
"Metropolis" director Fritz
55A
Transparent attempt to garner goodwill... and a literal description of this puzzle's highlighted pairs of answers (18A & 28A, 20A & 23A, 40A & 43A, 68A & 70A)
62A
Cooling gel
63A
Black-light gas, handy for alphabet books
64A
Dutch cheese
65A
___ spell (rest)
66A
___ the Giant of "The Princess Bride"
67A
Utah ski resort above Snowbird
68A
Delicacy (70A)
69A
"Twilight" author Stephanie
70A
Brightly colored (68A)
Down
1D
Type of smartphone game purchases
2D
Low point
3D
Not in port
4D
Dr. Jekyll's alter ego
5D
Tic-tac-toe winning line
6D
Gives one-star, say
7D
"I have no ___..."
8D
Handicraft website
9D
Didn't stand
10D
Attempt to get
11D
"Alien" and "Edda," for two
12D
Stock unit
13D
Cleared of data
21D
VCR go-withs
24D
Stay out of sight
26D
Increase excitement, with up
27D
Staple of the high life?
29D
Prefix with "-right" and "-rock"
30D
Louvre Pyramid architect
31D
"My time ___ come"
32D
"Man ___ Mancha"
33D
Indian flatbread
34D
"Gorillas in the ___"
37D
Length x width
38D
Home of the Munch Museum
39D
It's best done high, they say
41D
Gandhi, for one
43D
Film in which Dwayne Johnson plays Maui
45D
Ophthalmologist's yardstick
46D
FranklinCovey product
49D
Ancient Palestinian ascetic
50D
Who famously said, "I used to be the next President of the United States"