I just gotta say, 19A doesn't translate to anything, lol. At least not in Spanish or related languages. So a lot of guessing happened there since I didn't pay enough attentiom to DMB in college :).
Don't worry, you didn't let us down or hurt us.
Card that "Weird Al" Yankovic carries in "Trapped In The Drive-Thru", for short
10A
Garfield's prop in an iconic comic strip
11A
Assistant of "viewers like you", for PBS funding
12A
Mad Men's Draper
13A
Line after a break, pt. 3
17A
College, in Camden
18A
Ready, or word that comes after "ready"
19A
"Pantala ___ Pampa" (Dave Matthews Band song whose title translates to "I have a snake in my pants")
21A
A long ways away, in terms of distance
22A
3-pointers, for short
23A
Line after a break, pt. 5
24A
Line after a break, pt. 4
25A
Get ready
Down
1D
Band whose album "To Be Kind" I listened to on my 16th birthday because I love to torture myself for fun
2D
Answer to the question "How do you know Chris Christie?", perhaps
3D
TIPHEDE and VINDUM, for two
4D
Southern half of a certain cuisine
5D
Have a lil' snooze
6D
"LESGOOOOOOOOOOOOOOOOOOOOOOO", in Lisbon
8D
Desires
10D
"I miss the old days when no on knew who I was, I could put someone in a trap and see if they had the will to survive. Now everyone just ignores the puzzles and immediately start yelling 'SHOW PUPPET' until they see my puppet, and then yell 'PUPPET ___' or 'PUPPET HYPE'" (@jigsaw_quotes tweet)
12D
"If you talk to me I will block you."
14D
de Armas of "El Internado: Laguna Negra", the show I'm watching in Spanish class