Legacy game: a tabletop game designed to be permanently altered through multiple game sessions. The subtitle for this puzzle is not a reference to any event in particular or in general; rather, it's an alternate example for 38A, except its full title is Betrayal Legacy (as opposed to Betrayal At House on the Hill). I would have included BHH or Risk in the clue, except neither original version is a "legacy game", while the other titles are true legacy games.
You and @maturin asked ... Did you know there are "bandages" for long distance runners that go specifically over the nipple? (I don't think I need to wholly explain the why)