1D: G(E)NOME; did you know that David the Gnome was originally a Spanish television show?!
2D: REM+[-w]AKE
3D: ONEDAY* (*an[-n]oyed)
4A: [-t]WER[-p]+EON
5A: T(OW)ARD<
6A: HER[-o]+E+S+Y; the original version of this clue tried to do something off the famous Apple "Think Different" commercial but the part of speech didn't fully sync up