I immediately put in NOB for 1A1AFirst word of a particular San Francisco district...or a trait of all hints to all words in this grid[---] as in Nob Hill, which also works entirely except that "base up" doesn't mean anything.
Just realised upon review that it's NOE1AFirst word of a particular San Francisco district...or a trait of all hints to all words in this grid[---] in the clues, not the answers. Don't mind me.